TheraWings Consulting

MABDESIGN MEMBER

About us

TheraWings Consulting is a translational research consulting company for the discovery and development of innovative medicines.

Field of application
  • antibodies
  • cellular immunotherapy
  • immunomodulators
  • biomarkers
Therapeutic application
  • hematology
  • infectiology
  • immunology
  • oncology
  • ophtalmology

Expertise

  • Expression and pathway analysis of target
  • quantification of target
  • Assay development in in-vitro & in-vivo models
  • Research exploratory companion biomarkers
  • Cell Isolation/selection
  • Leukophoresis
  • Cell population isolation
  • Screening & Identification
  • Therapeutic libraries
  • In silico
  • In-vivo models
  • In-vitro & ex-vivo models
  • Indication searching
  • Biophysical profile
  • Binding & Affinity
  • Potency & Specificity
  • Epitope mapping
  • Functional effects
  • ADCC, ADCP & CDC
  • Antigen density target
  • Internalization
  • Pharmacology & Biological activity
  • PK/PD bioavailability
  • Mode of Action
  • Therapeutic efficacy
  • Safety
  • Immunogenicity
  • Hypersensitivity & allergies
  • Immunotoxicology
  • Specificity
  • Manufacturability
  • Production quality
  • CMC feasibility
  • Cell activation
  • Avidity testing
  • Cell-based activation (APCs, AAPCs)
  • Bead-base activation
  • Antibody-based activation
  • Ex-vivo activation (cell transfer)
  • In-vivo activation (in human transgenic mouse models)
  • Engineering
  • ADC
  • Protein scaffolds
  • Fragments
  • Multi-, bispecific
  • Fc-fusion proteins
  • Indication Prioritization
  • Antibody humanization
  • Affinity maturation
  • Proof of concept
  • Pharmacology potency
  • Exploratory toxicology
  • in-vitro & ex-vivo models
  • in-vivo models
  • Cell expansion
  • Gas permeable bags
  • G-Rex bioreactors
  • Wave-mixed bioreactors
  • Mechanism/Function
  • Mechanism of action
  • Safety
  • PK/PD features
  • Indication Identification
  • Exploratory toxicology
  • Drug-Target interaction
  • Level of response duration
  • Specificity
  • Surrogate markers
  • Predictive biomarkers
  • Treatment efficacy
  • Population stratification
  • Risk/benefit profile
  • Disease progression / follow-up
  • Master Cell Bank
  • Production
  • Cell Line development
  • Clone selection
  • Characterization
  • Storage
  • Analytical development
  • Cell Culture
  • Media composition
  • Bioreactor conditions
  • Cell expansion
  • Wave-mixed bioreactors
  • Stirred tank reactors

Category

  • Service

Contact