
TheraWings Consulting
MABDESIGN MEMBER
About us
TheraWings Consulting is a translational research consulting company for the discovery and development of innovative medicines.
Field of application
- antibodies
- cellular immunotherapy
- immunomodulators
- biomarkers
Therapeutic application
- hematology
- infectiology
- immunology
- oncology
- ophtalmology
Expertise
- Expression and pathway analysis of target
- quantification of target
- Assay development in in-vitro & in-vivo models
- Research exploratory companion biomarkers
- Cell Isolation/selection
- Leukophoresis
- Cell population isolation
- Screening & Identification
- Therapeutic libraries
- In silico
- In-vivo models
- In-vitro & ex-vivo models
- Indication searching
- Biophysical profile
- Binding & Affinity
- Potency & Specificity
- Epitope mapping
- Functional effects
- ADCC, ADCP & CDC
- Antigen density target
- Internalization
- Pharmacology & Biological activity
- PK/PD bioavailability
- Mode of Action
- Therapeutic efficacy
- Safety
- Immunogenicity
- Hypersensitivity & allergies
- Immunotoxicology
- Specificity
- Manufacturability
- Production quality
- CMC feasibility
- Cell activation
- Avidity testing
- Cell-based activation (APCs, AAPCs)
- Bead-base activation
- Antibody-based activation
- Ex-vivo activation (cell transfer)
- In-vivo activation (in human transgenic mouse models)
- Engineering
- ADC
- Protein scaffolds
- Fragments
- Multi-, bispecific
- Fc-fusion proteins
- Indication Prioritization
- Antibody humanization
- Affinity maturation
- Proof of concept
- Pharmacology potency
- Exploratory toxicology
- in-vitro & ex-vivo models
- in-vivo models
- Cell expansion
- Gas permeable bags
- G-Rex bioreactors
- Wave-mixed bioreactors
- Mechanism/Function
- Mechanism of action
- Safety
- PK/PD features
- Indication Identification
- Exploratory toxicology
- Drug-Target interaction
- Level of response duration
- Specificity
- Surrogate markers
- Predictive biomarkers
- Treatment efficacy
- Population stratification
- Risk/benefit profile
- Disease progression / follow-up
- Master Cell Bank
- Production
- Cell Line development
- Clone selection
- Characterization
- Storage
- Analytical development
- Cell Culture
- Media composition
- Bioreactor conditions
- Cell expansion
- Wave-mixed bioreactors
- Stirred tank reactors
Category
- Service
Contact
- Claudine VERMOT-DESROCHES
CEO & CSO - Allée des Terrasses - Bâtiment G 69570 Dardilly
- +33 (0)6 71 52 94 02
- claudine.vermot-desroches@therawings.com
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