Advanced Instruments

MABDESIGN MEMBER

About us

Advanced Instruments is dedicated to increasing productivity and ensuring quality in the biotechnology, pharmaceutical, clinical and food & beverage industries. With a focus on innovations that anticipate and overcome customer pain points, we help our customers deliver greater drug yields, better patient care and ensure food safety.

Know-how

Osmolality / Cell Line Development / Cloning

Business offer

Osmometers:
Whether you need insight into process development, patient health, or product quality, Advanced Instruments osmometers deliver unmatched quality, performance, and reliability.
Our easy-to-use instruments are thoughtfully optimized for biotech, clinical and food & beverage labs, and readily fit into any workflow and include a range of connectivity options.

Cell Line Development
We accelerate cell line development workflows from initial discovery to scale-up and manufacturing of new biological therapies
From single-cell cloning and colony outgrowth to the establishment of a master cell bank, cell line development technologies from Advanced Instruments streamline the collection of evidence for credible IND submissions.

Field of application
  • antibodies
  • cellular immunotherapy

Expertise

  • Expression and pathway analysis of target
  • quantification of target
  • Assay development in in-vitro & in-vivo models
  • Gene modification / Transduction
  • Retroviral & lentiviral vectors
  • Transposon/transposase
  • mRNA electroporation
  • CRISPR/Cas9
  • GMP compliance
  • Master Cell Bank
  • Production
  • Cell Line development
  • Clone selection
  • Characterization
  • Storage
  • Analytical development
  • Cell Culture
  • Media composition
  • Bioreactor conditions
  • Gene modification / Transduction
  • Retroviral & lentiviral vectors
  • Batches production type
  • Mammalian
  • Insect
  • Yeast
  • Bacterial
  • GMP compliance
  • Pilot Batches
  • Tests
  • Optimization
  • Scale-Up process
  • Process optimization & validation
  • Volume
  • Preclinical / Tox
  • Low volume (< 200 L)
  • High volume (200 – 2000 L)
  • Very high volume (> 2000 L)
  • Commercial
  • USP (Scale-Up)
  • Cell expansion
  • Inoculation
  • Low volume containers to Bioreactors
  • DSP (Recovery)
  • Harvest
  • Filtration
  • Purification
  • Fill & Finish
  • Aseptic filling
  • Lyophilization
  • Stability Assessment
  • Physical & chemical profile
  • Shear/shaking
  • Viscosity
  • Photostability
  • pH
  • Freeze/thaw
  • Heat/degradation
  • Aggregation
  • Cell line analytical development
  • Host cell proteins
  • Viral clearance
  • Contaminants detection
  • Biosafety & Bioanalysis
  • Toxicology
  • PK/PD features
  • Impurities detection
  • Batch release test
  • Chemical, physical, biological test
  • Quality control test support
  • Formulation
  • Dose
  • Stability
  • Excipients
  • Adjuvants
  • Sterilization
  • Lyophilization
  • Storage stability
  • Phase I
  • Phase II
  • Phase III
  • Phase IV
  • Regulatory Filing
  • Pharmacology

Category

  • Technology Supplier

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