ABL Lyon

MABDESIGN MEMBER

About us

ABL Lyon offers its expertise for the evaluation of immunotherapies in the detection & quantification of soluble Biomarkers & cell-based assays.

Know-how

Luminex, Simoa, Vidas, Flow cytometry, ELISpot

Business offer

The largest immuno-assay platform offer in Europe.
Monitoring the immune response in a regulatory compliant setting is our expertise at ABL. We support dozens of preclinical and clinical studies to evaluate the safety and efficacy of monoclonal antibodies (mAbs), immune-checkpoint inhibitors ,vaccines, Antibody Drug Conjugates (ADCs), Chimeric Antigen Receptor T cells (CAR-T cells) and several other candidate immunotherapies.

Field of application
  • antibodies
  • cellular immunotherapy
  • immunomodulators
  • therapeutic vaccines
  • biomarkers
Therapeutic application
  • hematology
  • infectiology
  • immunology
  • oncology
  • Neurobiology

Expertise

  • Target Selection & Validation
  • Assay development in in-vitro & in-vivo models
  • Research exploratory companion biomarkers
  • Immunotherapy Lead Generation
  • Functional effects
  • ADCC, ADCP & CDC
  • Antigen density target
  • Pharmacology & Biological activity
  • PK/PD bioavailability
  • Mode of Action
  • Therapeutic efficacy
  • Safety
  • Immunogenicity
  • Immunotoxicology
  • Preclinical biomarkers
  • Mechanism/Function
  • PK/PD features
  • Drug-Target interaction
  • Specificity
  • Surrogate markers
  • Research exploratory Companion biomarkers
  • Animal biomarkers
  • Human biomarkers
  • Predictive biomarkers
  • Treatment efficacy
  • Population stratification
  • Risk/benefit profile
  • Disease progression / follow-up
  • CMC
  • GLP compliance
  • Quality Assurance, Quality Control & Analytical process
  • Biosafety & Bioanalysis
  • PK/PD features
  • Clinical Trials
  • Phase I
  • Phase II
  • Phase III
  • Phase IV
  • Clinical biomarkers
  • Post-Market Surveillance
  • Companion biomarkers
  • Treatment efficacy
  • Treatment monitoring
  • Toxicity

Category

  • Service
  • Technology Supplier

Contact